Post-Operative Pain
Conditions
Brief summary
Hospitals, Qena, Egypt in period between May 2020 to May 2021.eighty patients was scheduled to elective laparoscopic cholecystectomy , divided Into two groups randomly using closed envelop method. Group IP lidocaine(40 patients ) received 200 ml saline containing 200 mg 2%lidocaine immediately after abdominal cO2 insufflation( pneumoperitoneum) the surgeon sprayed the total solution on the upper surface of the liver under the right subdiaphragmatic space, left subdiaphragmatic space and around the cholecystectomy site , all patients were maintained in trendelenberg position. At the end of the laparoscopic procedure, group indomethacin (40 patients) recived two 100 mg indomethacin rectal suppositories 2 hours prior to surgery
Interventions
two 100 mg indomethacin rectal suppositories 2 hours prior to surgery
200 ml saline containing 200 mg 2%lidocaine intraperitoneal insilltation
Sponsors
South Valley University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
* .ASA physical status 1-2 patients. * 18-60 years old .
Exclusion criteria
* using or allergic to nonsteroidal anti inflammatory drugs (NSAIDs) or aspirin . * history of serious hepatic disease. * renal or gastrointestinal disease. * bleeding disorder. * body mass index BMI \<18 or ˃30 m2/kg. * history of abdominal surgery or chronic pain disorder other than gallbladder. * disease or allergy to lidocaine.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| VAS scores postoperative | 24 hours posoperative | a standard 10-cm VAS was used, where one end of the scale represented no pain (0 cm), and the other end the most severe pain imaginable (10 cm), the distance in centimeters being taken as the pain score |
| postoperative opoiods analgesics requirements | 24 hours postoperative | we used (iv pethidine )whenever the patient complained of pain. IV pethidine injection 25-50 mg was given as rescue analgesic whenever the patient experienced pain ≥ to 5 VAS |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Pain starting time after surgery and Pethidine required first time. | 24 hours postoperative | Pain starting time after surgery and Pethidine required first time. |
Countries
Egypt
Outcome results
None listed