Chronic Ulcer, Healing Ulcer
Conditions
Keywords
Healing Ulcer, Chronic Ulcer, Musa sapientum, Lemongrass
Brief summary
To evaluate the activity of a gel composed of 10% peel powder of unripe banana (Musa sapientum) combined with lemongrass (Cymbopogon citratus) oil, at 0.1% concentration, in patients with chronic ulcers.
Detailed description
Purpose: To evaluate the activity of a gel composed of 10% peel powder of unripe banana (Musa sapientum) combined with lemongrass (Cymbopogon citratus) oil, at 0.1% concentration, in patients with chronic ulcers. Methods: This is a clinical, individual, analytical, interventional, longitudinal, prospective, controlled study with convenience sampling. Three groups will be used, as follows: control group 1 (CG1) with 7 participants will be treated with collagenase, control group 2 (CG2) with 7 participants will be treated with a gel composed of 10% unripe banana peel powder, and study group (SG) with 11 patients will be treated with the abovementioned gel combined with lemongrass oil at 0.1% concentration. The ulcer areas will be analyzed once a week for 4 weeks. Afterward, wound areas will be measured and the obtained data will be subjected to statistical analysis.
Interventions
BIOLOGICALgel combined with lemongrass (Cymbopogon citratus) oil at 0.1% concentration
It is a gel that was used in chronic ulcers healing
BIOLOGICALCollagenase ointment
Participants who were subjected to a standardized treatment (collagenase ointment)
BIOLOGICALGel with 10% peel powder of unripe banana
Participants who used a gel made of 10% peel powder of unripe banana (M. sapientum),
Sponsors
Universidade do Vale do Sapucai
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Intervention model description
Twenty-five people, regardless of gender, participated in this study. The patients were divided into 3 groups (Control 1, Control 2 and, Study Group). The Control Group 1 (CG1) consisted of seven participants who were subjected to a standardized treatment (collagenase ointment was selected for this treatment), the Control Group 2 (CG2) accounted for seven participants who used a gel made of 10% peel powder of unripe banana (M. sapientum), and the Study Group (SG) involved eleven participants who used the abovementioned gel combined with lemongrass (Cymbopogon citratus) oil at 0.1% concentration.
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* presence of chronic ulcers, * 18 years of age and older
Exclusion criteria
* Patients who had any type of allergic reaction to the study products during treatment
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Delimitation of the wound area | 3 month | To delimit the wound area, plastic and a fine-tipped pen will be used to outline the edge of the wound. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Digitalizing drawing wounds measurements | 3 months | All collected measurements (drawings) were scanned and saved in JPEG format and the areas were calculated using the ImageJ® software13. The ImageJ® was set to measure the area in centimeters, with a pixel of 118.67, establishing a fixed value. The areas were calculated individually in the software and the values were saved in an Excel spreadsheet. |
Countries
Brazil
Outcome results
None listed