Primary Immunodeficiencies in Costa Rican Adults

CASE SERIES OF PRIMARY IMMUNODEFICIENCIES IN ADULTS DIAGNOSED IN TWO HOSPITALS OF THE TERTIARY LEVEL OF CARE OF THE COSTA RICAN SOCIAL SECURITY Fund, 2017-2018

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04963660

Enrollment

137

Registered

2021-07-15

Start date

2018-11-11

Completion date

2019-11-11

Last updated

2021-07-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary Immune Deficiency in Adults

Brief summary

Primary immunodeficiencies represent a underdiagnosed group of rare diseases which if diagnosed well and in time can be treated in an efficient manner and prevent complications that may affect the quality of patients life in an severe manner. Neither in Costa Rica nor in Central America studies or national registries regarding the prevalence and characterization of primary immunodeficiencies in adult patients exist up to now. This study reflects for the first time the epidemiologic situation of primary immunodeficiencies in a Central American country, characterizing adult patients diagnosed with primary and idiopathic immune disorders treated in two specialized immunodeficiency clinics in Costa Rica.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

12 Years to 100 Years

Healthy volunteers

Inclusion criteria

* All patients from adult primary immunodeficiency clinics will be included.

Exclusion criteria

* Patients with HIV * Proven secondary immunodeficiencies.

Design outcomes

Primary

Measure	Time frame	Description
Clinical manifestations of all adult patients diagnosed with primary and idiopathic immune defects	1 year	Describe the clinical manifestations of all adult patients diagnosed with primary and idiopathic immune defects attended in the primary immunodeficiency clinics of the Hospitals Mexico and Dr. Rafael Ángel Calderón Guardia during the study period.

Secondary

Measure	Time frame	Description
organic complications	1 year	Record organic complications secondary to immunodeficiency status.
type and degree of immunodeficiency	1 year	Differentiate the type and degree of immunodeficiency of each patient.
bacteria present in upper airways	1 year	•Report the colonizing bacteria present in the cultures of the upper airways of the patients requested in the initial approach.
characterization of immunodeficient patients	1 year	Characterize immunodeficient patients using sociodemographic and health variables.
Concordances between clinical manifestations and literature	1 year	•Establish concordances between the clinical manifestations of the group of patients under study with those described in the literature according to the different pathologies.
pathonges that cause infectious	1 year	Report isolated pathogens that cause infectious manifestations in patients.

Countries

Costa Rica

Outcome results