Asthma, Asthma-COPD Overlap Syndrome, COPD
Conditions
Keywords
COPD, Asthma-COPD Overlap Syndrome, Asthma
Brief summary
There are few studies about immunological explorations in COPD. Because of the complications of lung biopsies, analyses are generally made on blood samples instead of lung tissue. No study tried to classify COPD vs Asthma vs ACOS. The investigators wondered if there were differences in biomarkers between these groups. The investigators decided to open a pilot-study among COPD patients followed in Amiens-University Hospital. Each patient will be examined and a blood-test will be performed.
Interventions
BPCO physical examinations
DIAGNOSTIC_TESTblood test
blood test in order to study immunologic markers
Sponsors
Centre Hospitalier Universitaire, Amiens
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* BPCO patients * ACOS patients * asthmatic patient without BPCO
Exclusion criteria
* infection * exacerbation * immunosuppressive treatment * immunosuppressive disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| identification specific blood immunologic marker for COPD | one hour | COPD biomarkers are blood immunologic markers |
Secondary
| Measure | Time frame |
|---|---|
| Complete blood count (CBC) Variation between COPD and asthmatic patients | one hour |
| c-reactive protein concentration variation between COPD and asthmatic patients | one hour |
| Plasma protein electrophoresis profile Variation between COPD and asthmatic patients | one hour |
Countries
France
Outcome results
None listed