Frailty
Conditions
Keywords
frailty, cognitive impairment, physical impairment, older adults
Brief summary
Frailty is a multidimensional condition due to reserve loss leading to physical and cognitive impairment that is very common in older adults; in fact, its incidence increases with age. Frail older adults present a high risk of adverse events such as disability, hospitalization and mortality. It is very important to check comorbidities and complications to reduce the incidence of cognitive and physical impairment.
Detailed description
Frailty is a multidimensional condition due to reserve loss leading to physical and cognitive impairment that is very common in older adults; in fact, its incidence increases with age. Frail older adults present a high-risk of adverse events such as disability, hospitalization and mortality. It is very important to check comorbidities and complications to reduce the incidence of cognitive and physical impairment; hence, clinical evaluation is the main goal to get an early diagnosis and a timely treatment for cognitive impairment. Considering this background, the study will investigate the effects of nutraceuticals and drug treatment on cognitive impairment in frail older adults. In this scenario, global cognitive function will be evaluated with Mini Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA) test and physical impairment with the Fried criteria and 5-metres gait speed test.
Interventions
To observe the effect on cognitive and physical impairment.
Sponsors
Study design
Eligibility
Inclusion criteria
* age \> 65 years; * a frailty status.
Exclusion criteria
* age \< 65 years. * no frailty status. * left ventricular ejection fraction \<25%, with previous myocardial infarction or previous PPCI or/and coronary by-pass grafting.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Montreal Cognitive Assessment (MoCA) | July 2021 | Global cognitive impairment |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| 5 metres gait speed test | July 2021 | Physical impairment |
Other
| Measure | Time frame |
|---|---|
| Correlation between MMSE/MoCA and 5 metres gait speed test | July 2021 |
Countries
Italy