The Impact of a Fast Diet and Calorie Mimetic Supplements on Epigenetic Aging

The Impact of Fasting Mimicking Diet Program and Calorie Mimetic Supplements on Epigenetic Aging

Status

UNKNOWN

Phases

Phase 2

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04962464

Enrollment

100

Registered

2021-07-15

Start date

2021-03-10

Completion date

2022-09-30

Last updated

2021-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aging

Brief summary

This is a prospective randomized clinical study of 50 patients to evaluate the fasting mimicking diet program by Prolon with a calorie mimetic supplement from Peak Human Labs. This study will be evaluating the effectiveness of the combined intervention over a three month program. The study will assess the effects that the program has on the participants' biological aging.

Interventions

DIETARY_SUPPLEMENTPeak Human Labs calorie mimetic supplement

Supplement

BEHAVIORALFasting Mimicking Diet

Diet

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

TREATMENT

Masking

SINGLE (Outcomes Assessor)

Intervention model description

prospective, randomized trial

Eligibility

Sex/Gender

ALL

Age

16 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Healthy individuals * Age \> 16 years

Design outcomes

Primary

Measure	Time frame	Description
Epigenetic Age Biomarkers	Change from baseline to 3 months	Outcome epigenetic age testing will test methylation at 850,000 spots on the DNA/

Secondary

Measure	Time frame
Body Mass Index	Change from baseline to 6 months

Countries

Canada

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026