Biliary Atresia
Conditions
Keywords
biliary atresia, kasai portoenterostomy, modified, cholangitis
Brief summary
the study of the effect o the hanging of the jejunal loop to the peri KPE Glisson capsule on the rate of bile drainage and requirement of liver transplantation
Detailed description
To evaluate the effect of anchoring jejunal loop to Glisson capsule of liver after completion of modified Kasai portoenterostomy (KPE) on the frequency of attacks of cholangitis and the overall incidence of native liver survival. Methods: Retrospective study included 29 infants diagnosed as biliary atresia (BA). They were subjected to modified KPE. Two subgroups were present. Group A included 16 infants and had KPE. Group B included 13 infants and had the assumed modification. Wider dissection of fibrous portal plate was considered in both groups. After completion of KPE, the jejunal loop anchored to Glisson capsule of liver at porta hepatis in group B.
Interventions
PROCEDUREkasai portoenterostomy
surgical creation of stoma between porta hepatis and jejunal loop
Sponsors
Tanta University
Study design
Allocation
NON_RANDOMIZED
Intervention model
SEQUENTIAL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
4 Weeks to 8 Weeks
Healthy volunteers
No
Inclusion criteria
* infants with biliary atresia diagnosed and treated before 60th day of age
Exclusion criteria
* infants older than 60 days
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| the total number of cholangitis | two years | the total attacks of chollangitis |
| number of native liver survivors | two years | the decrease of the need of liver transplantation in children with biliary atresia |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| early improvement of liver functions | 6 months | normalization of liver function |
Countries
Egypt
Contacts
Primary ContactMohammad Khirallah
Outcome results
None listed