Skip to content

Promoting Cervical Cancer Screening Through the Advocacy of Screened Women

Pilot of a Network-driven, Advocacy Intervention to Promote Cervical Cancer Screening in Uganda

Status
Completed
Phases
Phase 2
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04960748
Enrollment
143
Registered
2021-07-14
Start date
2021-08-30
Completion date
2022-04-25
Last updated
2022-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cervical Cancer Prevention

Keywords

cervical cancer screening, prevention advocacy, group intervention, Uganda, social networks

Brief summary

This study pilots a 7-session group intervention among 40 screened women, 20 of whom will be randomly assigned to take part in the intervention, and 20 to the wait-list control. Assessments will be administered at baseline and month 6 to index participants as well as up to three unscreened female social network members of each index participant (up to 120 total). The primary outcome is CC screening among participating social network members.

Detailed description

Cervical cancer (CC) is the most common cancer and accounts for \ 25% of all cancer related deaths among women in Uganda, which has one of the highest incidence rates in the world. Adding to the burden is the general lack of knowledge about, and social stigma towards CC and its screening in Uganda, where lifetime CC screening is estimated to be as low as 5%. There is a dire need to increase CC screening in Uganda to ensure timely and lifesaving treatment, as well as the need to enhance the capacity to conduct behavioral and health services research related to CC and other stigmatizing conditions among local researchers and service providers. Accordingly, the proposed intervention pilot study seeks to (1) empower women who have been screened for CC, to advocate for CC screening and early treatment among women in their social networks, and (2) engage and train local public health researchers and programmers. The proposed intervention draws on theories of social diffusion, cognitive consistency, and social influence, and the investigator's recently developed and tested group intervention that mobilized people living with HIV in Uganda to successfully act as change agents for HIV prevention within their social networks. The intervention actively targets internalized stigma, disclosure decision making, healthy living, and advocacy communication skills. This study will pilot the intervention among 40 screened women, 20 of whom will be randomly assigned to take part in the intervention, and 20 to the wait-list control. Assessments will be administered at baseline and month 6 to index participants as well as up to three unscreened female social network members of each index participant (up to 120 total). The primary outcome is CC screening among participating social network members. The primary aims of the study are to assess the feasibility, acceptability and preliminary efficacy of the group intervention to promote CC screening and treatment; identify characteristics associated with successful advocacy; and increase local capacity for conducting public health research on CC control and use of social network-based intervention and measurement methods.

Interventions

BEHAVIORALWOMEN FIGHTING TO STOP CERVICAL CANCER

The group intervention draws on theories of social diffusion, cognitive consistency, and social influence, and our own recently developed and tested group intervention that mobilized people living with HIV in Uganda to successfully act as change agents for HIV prevention within their social networks. The intervention actively targets internalized stigma, disclosure decision making, healthy living, and advocacy communication skills. The ultimate goal of the program is to encourage female social network members to get screened for cervical cancer.

Sponsors

Makerere University
CollaboratorOTHER
Rays of Hope Hospice Jinja
CollaboratorUNKNOWN
African Palliative Care Association
CollaboratorUNKNOWN
RAND
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE

Intervention model description

randomized controlled trial of parallel groups

Eligibility

Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* age 18 years or older * has been previously screened for cervical cancer * has told at least one woman in her social network about her cervical cancer screening experience

Exclusion criteria

* unstable medical status (e.g., advance disease stage that calls into question her ability to complete the 6-month study)

Design outcomes

Primary

MeasureTime frameDescription
Proportion of social network members who report cervical cancer screeningpast 6 monthscervical cancer screening among women in social network

Secondary

MeasureTime frameDescription
Proportion of index participants who self-report engagement in cervical cancer (CC) prevention advocacypast 6 monthsdiscussing cervical cancer and encouraging CC screening with women in social network

Countries

Uganda

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 12, 2026