Early Childhood Caries
Conditions
Keywords
early childhood caries
Brief summary
This study aimed to evaluate the levels of interleukin 10, interleukin 6, interleukin 32 and tumor necrosis factor-alpha (TNF-α) in saliva of children with early childhood caries.
Detailed description
Fifty six children ( 28 with early childhood caries and 28 without early childhood caries ; age range 3-6 years) will be recruited for the study. Probing pocket depth (PPD), gingival index (GI) and plaque index (PI) will be recorded and saliva samples will be collected. Interleukin-32, Interleukin-10, Interleukin-6 and TNF-α will be analyzed in saliva samples by ELISA.
Interventions
DIAGNOSTIC_TESTELISA
Enzim linked immunoabsorbant assay
Sponsors
Aydin Adnan Menderes University
Study design
Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
3 Years to 70 Months
Inclusion criteria
* Children with untreated early chilhood caries * Age between 3 and 6 years
Exclusion criteria
* Having a systemic problem or mental retardation * Children with treated caries
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| IL-32 | Baseline | Interleukin- 32 level |
| IL-10 | Baseline | Interleukin- 10 level |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| IL-6 | Baseline | Interleukin- 6 level |
| Tnf-Alpha | Baseline | Tnf-alpha level |
Countries
Turkey (Türkiye)
Outcome results
None listed