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A Multi-Center Data System and Collaborative Network in China for Severe Infection and Sepsis Children

Establishment of a Multi-Center Big Data System for Severe Infection and a Collaborative Network on Sepsis in Chinese Children

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04955210
Enrollment
5000
Registered
2021-07-08
Start date
2022-04-30
Completion date
2026-12-31
Last updated
2026-03-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Critical Illness, Severe Sepsis

Keywords

Sepsis, Critical Illness, severe infection

Brief summary

1\. To research the current situation of severe infection in children in China, and to investigate the incidence, prognosis and disease burden of severe infection in children in different regions of China. 2. Establish the risk prediction model and diagnosi model of severe infection in children, and verify the accuracy of the model in multi-center; 3. To study the effectiveness and safety of different treatments in real diagnosis and treatment, and to evaluate the efficacy of subgroups under different ages and high risk factors.

Detailed description

1.Children between 0 and 18 years old. 2.Severe pneumonia and/or sepsis.Patients were included who meet the guidline for diagnosis and treatment of community-acquired pneumonia in Children (2019) issued by the National Health Commission of the people's Republic of China and/or who meet the International Guide to the 2020 campaign to Save sepsis: management of septic shock and sepsis-related organ dysfunction in children. 3.notifiable infectious diseases.4.The researcher believes that he is not suitable to participate in other situations in this study.5.Participants in other clinical trials in the same period.

Interventions

OTHERNot applicable(Cohort study)

This is a prospective observational study and does not include interventions.

Sponsors

Children's Hospital of Fudan University
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
29 Days to 18 Years
Healthy volunteers
No

Inclusion criteria

1. Children between 0 and 18 years old. 2. Severe pneumonia and/or sepsis.

Exclusion criteria

1. notifiable infectious diseases. 2. The researcher believes that he is not suitable to participate in other situations in this study. 3. Participants in other clinical trials in the same period.

Design outcomes

Primary

MeasureTime frameDescription
survival ratewithin 28 days after they discharged from PICUThe survival rate of children in 28 days after their discharged from PICU

Secondary

MeasureTime frameDescription
length of stay in PICUwithin 28 days after they discharged from PICUTime from PICU admission to discharge

Countries

China

Contacts

CONTACTGuoping Lu
13788904150@163.com13788904150
PRINCIPAL_INVESTIGATORGuoping Lu

The Children's Hospital of Fudan University

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 17, 2026