Analgesia
Conditions
Brief summary
The aim of the study is to compare the efficacy of T2, T3 sympathetic block using thermal radiofrequency versus chemical neurolysis in postmastectomy pain syndrome using perfusion index derived from pulse oximetry.
Detailed description
Postmastectomy pain is a chronic pain condition with neuropathic nature. Several drugs and methods are used for its management. This study was designed to compare the efficacy of both thermal radiofrequency and chemical neurolysis in management of postmastectomy pain through using perfusion index derived from pulse oximetry.
Interventions
PROCEDUREThermal Radiofrequency
Radiofrequency lesioning at level of T2 and T3 using 80°c for 120 seconds
PROCEDUREChemical Neurolysis
injection of 1.5 ml of the chemical neurolytic agent (phenol in saline 8%) at each level
Sponsors
National Cancer Institute, Egypt
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* Female patients with postmastectomy pain syndrome * ≥ Age 18 years * ASA II-III
Exclusion criteria
* patient refusal * coagulation defects * abnormal kidney or liver functions * local infection at site of injection * bone metastases * severe cardiorespiratory disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Visual analogue score | up to 24 weeks | minimum score 0 and maximum score 10 |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Perfusion index trend | procedure time | measuring the change in perfusion index in the ipsilateral limb after the procedure compared to pre-procedural |
| Opioid consumption | up to 24 weeks | average opioid consumption |
Countries
Egypt
Outcome results
None listed