Thyroiditis, Autoimmune
Conditions
Brief summary
Some women at reproductive age have positive antithyroid antibodies (ATAs). Thyroid peroxidase antibody (TPOAb) and thyroglobulin antibody (TgAb) are the most common ATAs. This study aimed to evaluate the impact of ATAs on maturation of women reproductive system and pregnancy outcomes.
Interventions
DRUGLT4
LT4 is used to improve the thyroid function of pregnant women.
Sponsors
First People's Hospital of Yuhang
Taizhou Women and Children's Hospital Affiliated to Wenzhou Medical University
Changxing People's Hospital
Second Affiliated Hospital, School of Medicine, Zhejiang University
Study design
Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 45 Years
Healthy volunteers
Yes
Inclusion criteria
* Age during 18-45y; * Women tested for TPOAb and/or TgAb, TSH, free T3, free T4, total T3 and total T4 during the 1st trimester of pregnancy
Exclusion criteria
* Multiple pregnancies; * Age \< 18 y or \> 40 y; * L-T4 or PTU intervention before pregnancy; * Other autoimmune diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence rate of pregnancy complications in women with or without thyroid antibodies | 1 year |
Countries
China
Contacts
Primary ContactMin Jin
Outcome results
None listed