Thoracolumbal Interfascial Plane Block Versus Erector Spinae Plane Block for Lumbar Posterior Decompression Stabilization

Comparison of Perioperative Analgesia Effectiveness Between Thoracolumbal Interfascial Plane Block With Erector Spinae Plane Block In Lumbar Posterior Decompression and Stabilization: A Study to Interleukin-6 and Interleukin-10 Plasma Concentration, Pain Scale, Total Opioid Consumption, and Cardiovascular Stability

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04951024

Enrollment

Registered

2021-07-06

Start date

2021-03-01

Completion date

2022-01-31

Last updated

2021-07-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lumbar Posterior Decompression

Keywords

Thoracolumbal Interfascial Plane Block, Erector Spinae Plane Block, Lumbar Posterior Decompression and Stabilization

Brief summary

This study aimed to found out The Comparison Of Perioperative Analgesia Effectiveness Between Thoracolumbal Interfascial Plane Block with Erector Spinae Plane Block In Lumbar Posterior Decompression and Stabilization.

Detailed description

This is a double blind randomized controlled trial. Forty subject will be recruited with non-probability consecutive sampling method. Subjects who meet all inclusion criteria and do not have exclusion criteria will be asked to sign the informed consent form before included in this study. Subjects will be randomized into two groups. The first group is the group who will get Bilateral Thoracolumbal Interfascial Plane Block after general anesthesia and the second group will be the group who will get Bilateral Erector Spinae Plane Block after general anesthesia. After surgery, pain scale, time to first morphine dose, total morphine consumption in 24 hours, cardiovascular stability and adverse events will be recorded for both group.

Interventions

PROCEDUREThoracolumbar interfacial plane (TLIP) Block

TLIP Block: Bilateral 20 ml 0.25 % Bupivacaine injected between multifidus and longissimus muscle with Ultrasound guidance.

PROCEDUREErector Spinae Plane (ESP) Block

ESP Block: Bilateral 20 ml 0.25 % Bupivacaine injected between the erector spinae muscles and transverse process with Ultrasound guidance.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

1. Age 18 - 65 years old 2. Patients schedule for elective posterior decompression and stabilization lumbar spine surgery 3. ASA I - III 4. Decompression and posterior stabilization's patients who didn't caused by infection or abscess

Exclusion criteria

1. Patients who refuse to participate in this study 2. Body Mass Index \< 18,5 kg/m2 and \> 27,0 kg/m2 3. Patient with history of chronic opioid 4. Patient with coagulation disorder 5. Patient with cognitive disorders 6. Infection at the injection area

Design outcomes

Primary

Measure	Time frame	Description
Change from baseline Interleukin-6 and Interleukin-10 at 6 hours after Lumbar Posterior Decompression and Stabilization	Before surgery and 6 hours after surgery	Measure by ELISA

Secondary

Measure	Time frame	Description
investigators will record total morphine dose needed in 24 hours	24 hours after surgery	investigators will record time to first morphine dose after surgery

Countries

Indonesia

Contacts

Primary ContactAida Rosita R Tantri

aidatantri@gmail.com0213143336

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 10, 2026