Novel Equation for Estimating Resting Energy Expenditure in Dialysis Patients

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04947839

Enrollment

200

Registered

2021-07-01

Start date

2021-03-18

Completion date

2022-07-08

Last updated

2022-09-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Equation, Peritoneal Dialysis, Resting Energy Expenditure

Brief summary

The energy and nutrition states are closely associated with dialysis patients' complications and outcomes. To reach the energy balance target, we need the accurate resting energy expenditure level of patients. Traditional equations do not focus on and applicable to peritoneal dialysis patients, so we aim to develop and validate an equation for estimating resting energy expenditure in peritoneal patients.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Peritoneal dialysis patients and hemodialysis patients * Dialysis length \>3 months * \>18 years old * Consented to participate in all aspects of the study

Exclusion criteria

* Acute complications to hospitalization 1 month prior to the study; * Acute or chronic infections, cancer, and other wasting diseases in the past year; * Thyroid dysfunction; * Acute onset of podagra; Musculoskeletal diseases; * Respiratory diseases (asthma, pleural effusion, pneumothorax, COPD); * History of hormonal drug use; * During pregnancy or lactation; * Can not maintain posture and complete the REE test.

Design outcomes

Primary

Measure	Time frame	Description
Novel equation development	March 18, 2021 to October 30, 2021	Developed equation for estimating resting energy expenditure in peritoneal dialysis patients
Novel equation validation	October 30, 2021 to December 30, 2021	Validate the novel equation with resting energy expenditure obtained by indirect calorimetry (IC).

Countries

China

Outcome results