Acute Appendicitis, Acute Appendicitis With Appendix Abscess, Acute Appendicitis Without Peritonitis, Acute Appendicitis With Rupture, Appendicitis Acute, Appendicitis Perforated, Appendicitis; Perforation
Conditions
Brief summary
Short Post-operative Antibacterial Therapy in Complicated Appendicitis: Oral Versus Intravenous is a prospective randomized controlled trial comparing 24 hour intravenous antibacterial therapy to 24 hour oral antibacterial therapy after surgery in complicated appendicitis.
Interventions
OTHEROral versus intravenous administration of antibacterial treatment
Mode of administration of antibacterial treatment
Sponsors
Tartu University Hospital
North Estonia Medical Centre
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Intervention model description
RCT
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
Patients diagnosed with acute appendicitis and are candidates for laparoscopic appendectomy.
Exclusion criteria
Patients with compromised immune system (HIV, diabetes), ongoing or completed radio-chemotherapy in past 5 years, prosthetic heart valve, vascular prosthesis, pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Infectious complications | 30 days |
Countries
Estonia
Contacts
Primary ContactEdgar Lipping, MD
Backup ContactSten Saar, MD, PhD
Outcome results
None listed