Gingivitis, Mouth and Tooth Diseases, Periodontal Diseases
Conditions
Keywords
Periodontitis, Gingivitis, Mouthwashes
Brief summary
Recent studies have shown that while mouthwashes exhibit antimicrobial properties against bacteria and their products, at the same time showing the cytotoxic effect on living cells in the mouth.29 To the best of our knowledge, there is no information about the toxicity effect of these two mouthwashes, which are highly preferred, on antimicrobial peptides secreted from the oral epithelium. Therefore, our aim in this study is to evaluate the effect of chlorhexidine and essential oil mouthwash on hBD2 and LL-37 in saliva.
Detailed description
Periodontal health continues with a balanced interaction of the oral microflora with the host defense line.
Interventions
DRUGundefined
Rinsing with mouthwashes
Sponsors
Istanbul Medeniyet University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
25 Years to 40 Years
Inclusion criteria
1. systemically healthy, 2. presence of ≥20 natural teeth, 3. agreement to participate in the study .
Exclusion criteria
1. known systemic illness, 2. smoking habit, 3. pregnancy/ lactation, 4. long-term use of anti-inflammatory drugs.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Rate of periodontal parametres changes | 6 Months | Incidence of Gingivitis |
Contacts
Primary ContactMustafa C Yavuz, PhD
Outcome results
None listed