Effect of the Posterior Ligamentous Complex on the Adjacent Segments Degeneration After Lumbar Surgery

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04946487

Enrollment

Registered

2021-06-30

Start date

2021-07-01

Completion date

2022-12-30

Last updated

2021-06-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lumbar Spinal Stenosis

Keywords

Adjacent Segment Degeneration, lumbar posterior ligamentous complex, posterior lumbar interbody fusion

Brief summary

To investigate whether destroying the adjacent posterior ligamentous complex (PLC) has an effect on adjacent segment degeneration (ASD) after L5/S1 posterior lumbar interbody fusion (PLIF)

Detailed description

Purpose: To investigate whether destroying the adjacent posterior ligamentous complex (PLC) has an effect on adjacent segment degeneration (ASD) after L5/S1 posterior lumbar interbody fusion (PLIF). Methods: This retrospective study was performed in patients who received L5/S1 PLIF with pedicle screw instrumentation for lumbar spinal stenosis with or without isthmic spondylolisthesis. They were divided into the total laminectomy group, which had destruction of the PLC of the adjacent segment, or partial laminectomy group, which did not. Vertebral slip, osteophytes, disk height, and range of motion were examined by plain radiography, and thickness of the ligamentum flavum (LF) and anteroposterior diameters of the lumbar vertebral body and spinal canal were assessed by magnetic resonance imaging (MRI). Disc degeneration and spinal stenosis on MRI scans were categorized. The incidence of ASD and clinical outcome were compared between the groups.

Interventions

PROCEDUREtotal laminectomy

Total laminectomy removes the posterior ligamentous complex (PLC) at the fusion and superior levels.

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

25 Years to 75 Years

Inclusion criteria

* typical clinical symptoms such as disabling low back or leg pain with or without neurological symptoms, intermittent claudication, with refractory to ≥6 months of strict conservative treatment; and L5/S1 single-level PLIF with pedicle screw instrumentation.

Exclusion criteria

* previous spine surgery, acute spinal fracture, infection, and tumor.

Design outcomes

Primary

Measure	Time frame	Description
the Incidences of adjacent segment degeneration	From the end of treatment to more than 8 years	the Incidences of adjacent segment degeneration

Contacts

Primary ContactZhuofu Li

840764209@qq.com15620610715

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026