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Effect of Antihypertensive Drugs on Glaucoma Patients

Effect of Antihypertensive Drugs on Glaucoma Patients

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04943107
Enrollment
200
Registered
2021-06-29
Start date
2021-05-01
Completion date
2022-12-31
Last updated
2021-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glaucoma

Brief summary

It has been reported that among Asian non-glaucomatous, antihypertensive medications were associated with retinal nerve fiber layer and ganglion cell-inner plexiform layer thickness. In order to explore whether antihypertensive medications would influence the neuropathy among glaucomatous population, we designed a cross-sectional observational study to analyze the retinal status among glaucoma patients with use of antihypertensive medication.

Detailed description

we designed a cross-sectional obeservational study to analyze the retinal status among glaucoma patients with use of hyertensive medication.

Interventions

OTHERno intervention

no intervention, only measurement of blood pressure, intraocular pressure, hypertensive history questionnaire, retinal imaging, optical coherence tomography examination etc..

Sponsors

Second Affiliated Hospital, School of Medicine, Zhejiang University
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* age no less than 18 years * best corrected visual acuity better than decimal 0.3

Exclusion criteria

* secondary glaucoma * secondary hypertension * glaucoma-related operation history * pregnancy or lactation period * uncooperative with retinal examination * severe opacity with refracting media in eye * severe retinal diseases and neuropathy * congenital retinal optic nerve abnormality * other systemic diseases that influence hypertension and glaucoma assessment

Design outcomes

Primary

MeasureTime frameDescription
retinal nerve fiber layer thicknesswithin 3 months from recruitmentretinal nerve fiber layer thickness measured by optical coherence tomography

Countries

China

Contacts

Primary ContactKaijun Wang, MD
wkj992@126.com+86 13600529217

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026