Selenium
Conditions
Brief summary
To evaluate the effects of exogenous selenium supplementation on autoimmune thyroiditis.
Detailed description
In patients with autoimmune thyroiditis， investigators compared changes in thyroid function, anti-thyroid peroxidase antibody, anti-thyroglobulin antibody, thyroid magnetic resonance T1-mapping values and metabolic indicatorsfrom baseline to the end of treatment (12 weeks)
Interventions
DRUGSelenium
selenium 100ug ，take it orally twice daily
Sponsors
Beijing Chao Yang Hospital
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Intervention model description
patients with Autoimmune thyroiditis
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* Men or women between the ages of 18 and 75 * Clinical diagnosis of autoimmune thyroiditis, serum TPOAb and TGAB positive * Thyroid function is normal, and no drugs affecting thyroid function such as Umetole and Serge have been used
Exclusion criteria
* The contraindications indicated in the Chinese instructions of the drug * Hypothyroidism, hyperthyroidism * Liver function impairment * Renal function impairment * Claustrophobia * Mental disorders
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| anti-thyroglobulin antibody changes | Changes from baseline and 3 months during follow-up | Changes from baseline and 3 months during follow-up |
| T1-mapping values of Thyroid MRI | Changes from baseline and 3 months during follow-up | Changes from baseline and 3 months during follow-up |
Countries
China
Contacts
Primary ContactJia Liu, MD
Backup ContactXiaomeng Sun
Outcome results
None listed