Opioid Misuse
Conditions
Brief summary
The primary hypothesis of this study is that at 3 months, there will be a higher proportion of intervention participants vs. control participants who report greater risk of harm from misuse of prescription opioids AND heroin.
Detailed description
This study's specific aims are to: Conduct a randomized controlled trial with 532 high-risk adolescents in 10 School Based Health Centers (SBHCs), to compare PlaySmart to attention/time control games, with assessments post- gameplay (6 weeks), and at 3, 6, and 12 months following enrollment to determine if PlaySmart: 1) increases proportion of participants who report a perception of great risk of harm from misuse of opioids at 3 months; and 2) decreases intentions to misuse opioids; 3) increases self-efficacy for refusing opioids; 4) prevents initiation of opioid misuse, at all time-points.
Interventions
BEHAVIORALPlaySmart
PlaySmart is designed to provide players with behavioral skills and knowledge through repetitive and engaging videogame play to target adolescent perception of risk of harm from initiating opioid misuse.
OTHERVideo Game Control
Participants in the control group will play another video game with no intended effect similar to PlaySmart.
Sponsors
Tyra Boomer
National Institute on Drug Abuse (NIDA)
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
16 Years to 19 Years
Healthy volunteers
Yes
Inclusion criteria
* Participants must: * 1\) preferably be enrolled in their high school's School-Based Health Center; * 2\) report NOT having engaged in any prior opioid misuse; * 3\) be at "high-risk" based on their report at baseline of past 30-day use of cigarettes, e-cigarettes, Juul, alcohol, marijuana (including synthetics), amphetamine, cocaine, benzodiazepines, ecstasy, bath salts, or any other misuse of non-opioid prescription drugs or use of non-opioid illicit drugs OR have a score of ≥1 on the PHQ-2 OR a score of ≥1 on the GAD-2 (both screening tools used by SBHA); * 4\) be willing to sit for 60 minutes/session to play the game; * 5\) be able to provide assent/parental/guardian consent (if under age 18).
Exclusion criteria
* Failure to meet any of the inclusion criteria.
Countries
United States
Contacts
PRINCIPAL_INVESTIGATORLynn E Fiellin, MD
Director, play2PREVENT Lab & Professor, BDS at Geisel School of Medicine at Dartmouth College
Outcome results
None listed