Efficacy of Dextrose Prolotherapy in Myofascial Pain Syndrome
Conditions
Keywords
Myofascial pain, dextrose prolotherapy, neck disability
Brief summary
Myofascial pain syndrome is characterized by the presence of hypersensitive points called trigger points that cause pain, tenderness, spasm, stiffness, limitation of movement, weakness, taut band within the muscle, and pain reflected by pressing in a muscle group or a single muscle. Prolotherapy is a regenerative treatment method in the treatment of chronic musculoskeletal pain, in which an irritating solution is injected, often hypertonic dextrose, into painful ligament and tendon attachments and adjacent joint spaces. In this study, it was aimed to examine the effect of prolotherapy application on pain, neck range of motion and neck disability in women with myofascial pain syndrome.
Interventions
DRUGInjection of dextrose, local anesthetic and saline to the myofascial trigger point
An injection of 5 ml of 5% dextrose prolotherapy using 2.5 ml 10% dextrose, 1 ml 2% local anesthetic (lidocaine), 1.5 ml 0.9% saline will be administered to the active group from at least 10 trigger points.
DRUGLocal anesthetic and saline injection to the myofascial trigger point
A total of 5 ml of solution created by using 4 ml of 0.9% saline and 1 ml of 2% local anesthetic (lidocaine) will be administered to the control group, with at least 10 trigger points.
Sponsors
Mustafa Kemal University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
FEMALE
Age
20 Years to 50 Years
Healthy volunteers
No
Inclusion criteria
* 60 women aged 20-50 years with a diagnosis of myofascial pain syndrome
Exclusion criteria
* Cervical radiculopathy, cervical degeneration, neck surgery or trauma in the last year, injection history for myofascial pain syndrome in the last 6 months, cognitive impairment and fibromyalgia, rheumatoid arthritis, hypothyroidism, diabetes mellitus
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Visual Analog Scale | First month post-treatment | 0-10 cm visual scale (0: no pain, 10: most severe pain) |
| Neck Disability Index | First month post-treatment | It measures the functional state of the neck by scoring between 0-5 points according to the severity of pain, consisting of 20 questions. |
| Neck joint range of motion measurement | First month post-treatment | Active neck range of motion, which shows the movement of the neck in all directions, is evaluated by goniometric measurement. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Side effects | Through study completion, an average of 6 month. | Edema, ecchymosis, hematoma, allergic reaction, exacerbation of pain, systemic or distant side effects |
Countries
Turkey (Türkiye)
Contacts
Primary ContactHalil Ogut, M.D.
Outcome results
None listed