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Comparison of ARDS COVID-19 (WHO) vs ARDS Influenza in the ICU

Clinical Outcomes and Characteristics of Critically Ill Patients With Influenza and COVID-19 Induced ARDS: a Retrospective, Matched Cohort Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04941092
Enrollment
157
Registered
2021-06-28
Start date
2021-06-01
Completion date
2021-07-10
Last updated
2022-07-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ARDS, COVID-19 Acute Respiratory Distress Syndrome, Influenza

Keywords

ards

Brief summary

Since the beginning of the SARS CoV 2 pandemia, the SARS CoV 2 was frequently compared with the seasonal influenza virus. However, few studies compared patients presenting acute respiratory distress syndrome (ARDS) induced by these viruses, with results being discordant. Our study means to compare mortality and morbidity of patients hospitalized in an intensive care unit (ICU) with ARDS induced by SARS CoV-2 and seasonal influenza.

Interventions

OTHERno intervention

no intervention, retrospective comparison

Sponsors

Central Hospital, Nancy, France
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* patients hospitalized in ICU * under mechanical ventilation * presenting an ARDS according to the Berlin definition * induced by either influenza or SARS CoV 2

Exclusion criteria

* pregnant women * mechanical ventilation\>48 hours before admission

Design outcomes

Primary

MeasureTime frame
mortalityat 28 days

Secondary

MeasureTime frame
length of stay in ICUat 28 days
length of mechanical ventilationat 28 days
length of vasopressorsat 28 days
length of extrarenal epurationat 28 days
amount of drugs for sedationat 28 days

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026