Bruxism
Conditions
Brief summary
Implant rehabilitation is a successful treatment option for edentulous patients. Decreasing bone loss around implants is an important target for all implantologists. It has been shown that pathological forces, such as bruxism, may in fact result in bone loss and eventual implant failure. Botilinium Toxin is a material of many clinical uses. Beside its cosmetic applications, it has been used in the treatment of masseter muscle hypertrophy. Purpose: To investigate the effect of botilinium toxin injection on biting forces, and its ultimate effect on peri-implant bone changes.
Interventions
Botox is a well known neurotoxin that is derived from the bacterium clostridium botulinium. Its therapeutic applications are variable and well documented, alongside its cosmetic applications. There are seven known serotypes of Botox, from A to G, but only two types; A &B, are available for medical and cosmetic uses.
Sponsors
British University In Egypt
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
DOUBLE (Caregiver, Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
45 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
* Patients with a partially edentulous mandible, Kennedy Class I configuration, who are indicated for rehabilitation with partial implant overdenture prostheses, and who complained of Bruxism.
Exclusion criteria
* The presence of notable facial asymmetry. * Severe malocclusion * Pregnancy * A history of any serious medical illness * Drug allergy.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in biting force | 12 months | Biting force measured using T-Scan |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Bone changes around implant | 12 months | Bone changes using 3D CBCT |
Countries
Egypt
Outcome results
None listed