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Study on the Trajectories of Rehabilitation Compliance in Stroke Patients

Study on the Trajectories of Rehabilitation Compliance in Stroke Patients Based on Latent Growth Mixture Model

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04939896
Enrollment
282
Registered
2021-06-25
Start date
2021-01-19
Completion date
2023-12-31
Last updated
2026-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke, Acute

Keywords

Rehabilitation, stroke, medical adherence, trajectory

Brief summary

To describe the general trajectories of rehabilitation compliance in first-onset stroke patients within 6 months, and to identify the heterogeneous development trajectory of different subgroups based on the mixed model of latent growth.To explore the predictors of different change tracks of rehabilitation compliance of stroke patients from the perspectives of biological, psychological and social factors, so as to provide the basis for formulating precise nursing intervention measures.

Detailed description

To describe the general trajectories of rehabilitation compliance in first-onset stroke patients within 6 months. To recruit first-onset stroke patients undergoing rehabilitation and collect the general data. Telephone follow-up at 2 weeks, 6 weeks, 8 weeks, 12 weeks and 24 weeks after the onset. Based on the biological-psychosocial medical model and literature, biological, psychological and sociological factors were screened. The patient rehabilitation adherence level in different periods was measured. Latent Growth Mixture Model (LGMM) was used to investigate the general trend of rehabilitation compliance in patients with first-episode stroke within 6 months. Latent Class Growth Analysis (LCGA) method in Latent Growth hybrid model was used to identify the track of heterogeneous change. Multivariate Logistic regression analysis was used to explore the predictors of different subgroups of change trajectories relative to other subgroups.

Interventions

OTHERobservation

Observed patients' compliance with rehabilitation at different time

Sponsors

Second Affiliated Hospital, School of Medicine, Zhejiang University
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Patients diagnosed with stroke by CT or MR; * Patients with first onset (within 14 days of onset); ③ limb dysfunction (muscle strength ≤4); ④ Age: ≥18 years old; ⑤ Awareness (NIHSS consciousness level ≤1 point); * Informed consent of patients.

Exclusion criteria

* Patients with deep vein thrombosis; * fracture patients; * a history of severe cardiopulmonary dysfunction and craniocerebral trauma; * recurrent stroke during the study; ⑤patients with severe mental disorders; ⑥ Mixed aphasia patients.

Design outcomes

Primary

MeasureTime frameDescription
Motor Functional Exercise Compliance Scale for Stroke PatientsWeek 2The full score is 56 points, and the higher the cumulative score of each item, the higher the level of compliance.

Countries

China

Contacts

PRINCIPAL_INVESTIGATORYuping Yuping, master

Nursing Department Second Affiliated Hospital of Zhejiang University School of Medicine

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Apr 24, 2026