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Fatigue and Kinematics During Isometric Activity of the Upper Limbs in Young and Older Adults

Relationship Between Perceive Effort, Physiological and Kinematic Changes During Upper Limbs Isometric Activity and Its Relationship With the Socio-demographic Characteristics

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04938791
Enrollment
60
Registered
2021-06-24
Start date
2021-10-01
Completion date
2022-02-28
Last updated
2022-03-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fatigue

Keywords

Respiration, Perceived, Kinematics, Performance

Brief summary

The aim of this study is to understand the relationship between perceived effort and physiological and kinematic variables caused by isometric activity of the upper limbs, as well as its relationship with socio-demographic characteristics, level of activity and quality of life.

Interventions

OTHERIsometric activity

Participants will do elevation of upper limbs and mantain a 90º degree flexion position in an unsupported way.

Sponsors

Escola Superior de Saude da Cruz Vermelha Portuguesa - Lisboa
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Healthy * Minimum age of 18 years;

Exclusion criteria

* Unable to provide written consent * History of heart, cardiovascular and / or respiratory disease, * Known untreated hypertension, cardiomyopathy, or exercise intolerance * Presence of cognitive or neurological disorders * Neuromuscular or orthopaedic disorder that limits the movement of the upper limb to 90° flexion or the maintenance of that position * BMI ≥ 40

Design outcomes

Primary

MeasureTime frameDescription
Change from Baseline in upper limb motion angular acceleration through inertial motion units (IMU) systemFrom baseline to end of activity, up to 15 minutesAngular acceleration (in m/s\^2) of the arm measured before and during activity to track small movements of upper limb during isometric activity
Change from Baseline in muscle action potential frequency through surface electromyography (sEMG)From baseline to end of activity, up to 15 minutesMuscle action potential frequency (in hertz - Hz) of surface electromyographic signal measured before and during activity to track muscular fatigue signs.
Change from Baseline in respiratory pattern through inertial motion units (IMU) from baseline and during activityFrom baseline to end of activity, up to 15 minutesAngular range of motion (in degrees) of rib cage and abdominal wall during upper limb activity measured before and during activity to track changes in respiratory pattern during activity
Change from Baseline in perceived effort on the Borg category-ratio 10-point scale (CR 10)From baseline to end of activity, up to 15 minutesThe perceived effort will be measured with Borg CR 10 scale. Possible scores range from 0 (no exertion at all) to 10 (extremely strong).
Change from Baseline in heart rateFrom baseline to end of activity, up to 15 minutesHeart rate (heart beatings per minute) measured before and during activity to track cardiovascular changes during activity.
Change from Baseline in respiratory rateFrom baseline to end of activity, up to 15 minutesRespiratory rate (respiratory cycles per minute) measured before and during activity to track changes in respiratory function during activity.
Change from Baseline in heart rate variability (HRV)From baseline to end of activity, up to 15 minutesInterval (in milliseconds) between consecutive heartbeats measured before and during activity to track changes in autonomic function during activity.
Change from Baseline in electrodermal activity (EDA)From baseline to end of activity, up to 15 minutesElectrical conductance (in microsiemens -µS) between two points of the hand over time measured before and during activity to track changes in autonomic function during activity.
Change from Baseline in muscle action potential amplitude through surface electromyography (sEMG)From baseline to end of activity, up to 15 minutesMuscle action potential amplitude (in millivolts - ms) in surface electromyographic signal measured before and during activity to track muscular fatigue signs.
Change from Baseline in muscle action potential duration through surface electromyography (sEMG)From baseline to end of activity, up to 15 minutesMuscle action potential duration (in milliseconds - ms) in surface electromyographic signal measured before and during activity to track muscular fatigue signs.

Secondary

MeasureTime frameDescription
Physical activity levelBefore isometric activityPhysical activity level will be measured using European Prospective Investigation into Cancer and Nutrition Physical Activity Questionnaire (EPIC-PAQ) that allows to estimate energy expenditure through self-report assessment of the intensity and average duration (per day, week and month) of physical activity performed by the participants in three distinct dimensions (professional, domestic and leisure). Participants are classified as ACTIVE if they perform: at least 150 minutes per week of moderate physical activity; OR at least 75 minutes per week of vigorous physical activity; OR at least 150 minutes per week of a combination of moderate-intensity activity. If they don't present any of the conditions described, they will be categorized as SEDENTARY.
Health StatusBefore isometric activityHealth Status will be measured with Medical Outcomes Study (MOS) Short Form Health Survey 36 Item version 2 which measure health status of populations and individuals. Possible scores range from 0 0 (worst health status) to 100 (best health status).

Countries

Portugal

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026