Age-related Cognitive Decline
Conditions
Brief summary
To test a 14-hour prolonged nightly fasting (PNF) protocol in a group of older adults (≥ 65 years old) with self-identified age-related cognitive decline (ARCD) on the primary outcome of neurocognitive function and performance as measured by objective outcomes. The investigators will use an 8-week single group pre-post pilot study design to measure outcomes related to neurocognitive function and performance and cardiometabolic risk factors (i.e., sleep disturbances, body mass index).
Interventions
OTHERPNF
PNF Participants will engage in 8 weeks of 14 hours per night fasting
Sponsors
Arizona State University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* 65 or older * Self-identified age-related cognitive decline (ARCD) * Has a text capable phone and access to wifi
Exclusion criteria
* Diagnosed with an eating disorder in the past 20 years * Works a night shift * Cannot participate in a 14 hour fast * Has diabetes
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Memory and Attention Phone Screener (MAPS) | 8 weeks | Cognitive Function and Performance Test. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Insomnia Severity Index (ISI) | 8 weeks | Scale to asses insomnia symptoms. The scale has a minimum of zero and maximum of 28 where zero would be absence of insomnia and 28 would be severe insomnia. |
| Mindful Eating Scale (MES) | 8 weeks | Scale to asses behaviors related to mindful eating. Each item has a minimum of zero and a maximum of 4 where 4 means less eating awareness. |
| Rapid Eating Assessment for Participants Scale (REAPS) | 8 weeks | Scale to asses eating behaviors. The scale has a minimum of 13 and a maximum of 39. Higher scores indicate higher diet quality. |
| Salivary Cortisol | 8 weeks | Measure of cortisol via participant saliva samples. |
| Body Mass Index (BMI) | 8 weeks | Self-reported body measurements . |
| Creature of Habit Scale (COHS) | 8 weeks | Scale to asses routine habits. Each item has a minimum of zero and a maximum of 4 where 4 means a more habitual nature. |
Countries
United States
Outcome results
None listed