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Construction and Application of a Risk Prediction Model Forepistaxis After Pituitary Tumor Resection

Construction and Application of a Risk Prediction Model Forepistaxis After Endoscopic Transsphenoidal Pituitary Tumor Resection

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04938401
Enrollment
1
Registered
2021-06-24
Start date
2021-07-02
Completion date
2023-12-31
Last updated
2021-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pituitary Tumor

Brief summary

(1) Objective to establish an evaluation system for predicting the risk of epistaxis after endoscopic transsphenoidal pituitary surgery( 2) Objective to determine the risk factors of epistaxis after endoscopic transsphenoidal pituitary adenoma surgery. Referring to domestic and foreign literature, combined with experts' opinions, the related risk factors that may cause postoperative nosebleed of pituitary adenoma are: 22 patients and surgical factors. 3) Objective to establish a risk prediction model of epistaxis after endoscopic transsphenoidal pituitary tumor resection. According to the occurrence of epistaxis, the patients in the modeling group were divided into epistaxis group and non epistaxis group. The risk factors of epistaxis were taken as the independent variable, and the occurrence of epistaxis was taken as the dependent variable. The variables with statistical significance in univariate analysis were included in the multivariate logistic regression model, and the risk prediction model of epistaxis after pituitary tumor resection was established by back LR method.(4) Objective to verify the risk prediction model of endoscopic transsphenoidal pituitary adenoma epistaxis. The validation model is used to validate the prediction model, and the Hosmer-Lemeshow degree is used to match the model. The area under the receiver operating characteristic curve (ROC) was used to evaluate the validity of the model.(5) Application of risk prediction model.

Interventions

None listed

Sponsors

Sir Run Run Shaw Hospital
CollaboratorOTHER
Zhejiang University
CollaboratorOTHER
Zhejiang Provincial People's Hospital
CollaboratorOTHER
Wang Ying supervisor nurse
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
14 Years to 90 Years

Inclusion criteria

Those who met the diagnostic criteria of pituitary tumor and received transsphenoidal endoscopic surgery during hospitalization; Patients with informed consent; Age ≥ 14 years old.

Exclusion criteria

quitters; patients with incomplete clinical data;

Design outcomes

Primary

MeasureTime frameDescription
Incidence of epistaxisup to 24 weeksOverall incidence of epistaxis

Contacts

Primary ContactYIing Wang
Ukuk007@126.com13588837622

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026