Thyroid Disease Pregnancy
Conditions
Brief summary
The investigators' aim is to enroll around 2000 patients from Taipei, Keelung, Linkou, Chiayi and Kaohsiung CGMH. All participants will receive universal thyroid function screening at 1st trimester, and those who was found to have hyperthyroidism or hypothyroidism will be referred to Endocrine department for further treatment. All participants will be followed at outpatient clinic, and their obstetric visit finding will be recorded. The maternal and neonatal outcomes will be analyzed.
Interventions
DRUGPTU 50 MG Oral Tablet
to treat if the patient has hyperthyroidism
DRUGLevothyroxin
to treat if the patient has hypothyroidism
Sponsors
Chang Gung Memorial Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 50 Years
Healthy volunteers
No
Inclusion criteria
* Pregnant women at first trimester (\< 14 weeks of gestational age)
Exclusion criteria
* None
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The prevalence thyroid dysfunction | 40 weeks | Hypothyroidism: defined as serum TSH \> 2.5U/mL and decreased fT4\*; Hyperthyroidism: defined as fT4 \> normal range\* and TSH undetectable \* Serum free T4 range varies according to trimesters. |
Countries
Taiwan
Contacts
Primary ContactTai-ho Hung, PhD
Backup ContactChen-ai Sung, MD
Outcome results
None listed