Low Level Light/Laser Therapy, Near Infrared Spectroscopy
Conditions
Keywords
Low level light/laser therapy, Near infrared spectroscopy
Brief summary
This study aims to investigate the circulation and oxygenation changes of deep tissue respond on low level light/laser therapy (LLLT) in the healthy population. The investigators used a self-made near infrared spectroscopy (NIRS) instrument to noninvasively monitor hemodynamic indicators of brain and forearm muscle groups, including total hemoglobin (\[tHb\]), and blood flow (BF) and oxygen consumption (VO2).
Detailed description
Low level light/laser therapy (LLLT) employs visible or near-infrared light generated from a laser or light emitting diode (LED) system. It has beneficial effects on a wide range of disease, including improving wound healing, reducing pain, improving memory, treat cancer, and many other human applications. This study aims to investigate the circulation and oxygenation changes of deep tissue respond on low level light/laser therapy (LLLT) in the healthy population. The investigators used a self-made near infrared spectroscopy (NIRS) instrument to noninvasively monitor hemodynamic indicators of brain and forearm muscle groups, including total hemoglobin (\[tHb\]), and blood flow (BF) and oxygen consumption (VO2). Then the investigators concluded the effect of LLLT, according to compare the difference between the experimental group and control group.
Interventions
PROCEDURELow-Level Laser Therapy
Use 810-nm-photosource to irradiate the participants' brain and forearm for 10 minutes with a water-cooling radiator to keep it at 25 ± 0.5 ℃.
Sponsors
Ting Li
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
20 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
* Healthy participants with no strenuous exercise or alcohol consumption prior to the test
Exclusion criteria
* having risk factors associated with cardiovascular disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Δ[HbO2] | through study completion, an average of 1 year | changes of oxyhemoglobin concentration |
| Δ[Hb] | through study completion, an average of 1 year | changes of deoxy-hemoglobin concentration |
| Δ[tHb] | through study completion, an average of 1 year | changes of total hemoglobin concentration |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Subcutaneous fat thickness | through study completion, an average of 1 year | the subcutaneous fat thickness of the forearm |
Countries
China
Outcome results
None listed