Risk Factors for Predictors of MACEs After RA-CABG

Risk Factors for Predictors of Major Adverse Cardiovascular Events After Coronary Artery Bypass Using Radial Artery Grafts

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04935086

Enrollment

370

Registered

2021-06-22

Start date

2021-06-30

Completion date

2021-11-30

Last updated

2024-12-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Artery Disease

Keywords

Risk Factors, CABG, Radial Artery, MACE

Brief summary

As the secondary choice of artery grafts, radial artery is more and more used to achieve multiple arterial revascularization in CABG. Risk factors for predictors of major cardiovascular adverse events (MACE) after CABG using radial-artery grafts (RA-CABG), however, remain uncertain. This case-control study aims to identify the baseline predictors of MACE after RA-CABG. We will collect the baseline characteristics and perioperative data of patients underwent RA-CABG from Jan. 2009 to Dec. 2019 in our single center. By reviewing the latest follow-up records, we will examine the correlation between the baseline characteristics and clinical outcomes (MACEs), then identify the independent risk factors for predictors of MACEs after RA-CABG.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Underwent CABG using at least a radial artery grafts from Jan.2009 to Dec.2019. with or without cardiopulmonary bypass , with or without concomitant procedure * Aged 18 and above at procedure * With any gender

Exclusion criteria

* With unavailable medical records

Design outcomes

Primary

Measure	Time frame	Description
7-day MACE-4	7 days post-CABG	a composite of all-cause death, myocardial infraction, stroke and repeat revascularization
30-day MACE-4	30 days post-CABG	a composite of all-cause death, myocardial infraction, stroke and repeat revascularization
1-year MACE-4	1 year post-CABG	a composite of all-cause death, myocardial infraction, stroke and repeat revascularization
3-year MACE-4	3 years post-CABG	a composite of all-cause death, myocardial infraction, stroke and repeat revascularization

Secondary

Measure	Time frame	Description
Stroke	7 days, 30 days, 1 year, and 3 years post-CABG	According to the 2017 Cardiovascular and Stroke Endpoint Definitions for Clinical Trials, including ischemic, hemorrhagic and unknown type.
MACE-3	7 days, 30 days, 1 year, and 3 years post-CABG	a composite of CV-death, myocardial infraction and stroke
Repeat revascularization	7 days, 30 days, 1 year, and 3 years post-CABG	According to the 2017 Cardiovascular and Stroke Endpoint Definitions for Clinical Trials, including any PCI and CABG.
All-cause death	7 days, 30 days, 1 year, and 3 years post-CABG	Death from any cause
CV-death	7 days, 30 days, 1 year, and 3 years post-CABG	Including death resulting from an acute myocardial infarction , sudden cardiac death, death due to heart failure, death due to stroke, death due to cardiovascular procedures, death due to cardiovascular hemorrhage, and death due to other cardiovascular causes
Myocardial infraction	7 days, 30 days, 1 year, and 3 years post-CABG	According to the 2017 Cardiovascular and Stroke Endpoint Definitions for Clinical Trials, including CABG-related MI, non CABG-related MI, silent MI and unknown type.

Countries

China

Outcome results