Multiple Sclerosis
Conditions
Keywords
multiple sclerosis, upper limb function, activity, participation
Brief summary
The upper extremity in people with Multiple Sclerosis (pwMS) has become a more popular research topic in recent years, with the increase in studies reporting widespread involvement. The aim of our study was to evaluate the upper extremity from multiple perspectives in early stage pwMS, to identify problems by comparing them with healthy individuals, and to examine the relationship of problems with activity and participation.
Interventions
None listed
Sponsors
Istanbul University - Cerrahpasa
Uğur OVACIK
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* MS diagnosis according to McDonald criteria * Relapsing Remitting MS clinical course type * 18-65 age range * Being able to understand and read Turkish
Exclusion criteria
* Having an MS attack in the last 3 months * To have done regular exercise for the upper extremity in the 6 months before starting the study * Having different neurological, orthopedic or cardiac problems other than MS * Being addicted to alcohol or drugs * Getting a score below 24 on the Mini Mental Test Scale * Having a spasticity of 3 or more according to the Modified Ashworth Scale
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Nine Hole Peg Test | baseline (on the predetermined assessment day) | To assess upper extremity function. Completing the test in a short time (seconds) indicates better upper extremity function. |
| Minnesota Manual Dexterity Test | baseline (on the predetermined assessment day) | To assess upper extremity function. Completing the test in a short time (seconds) indicates better upper extremity function. |
| ABILHAND | baseline (on the predetermined assessment day) | To assess for performance of activity. Score range 0-46 point, higher scores mean a better outcome. |
| Motor Activity Log-28 | baseline (on the predetermined assessment day) | To assess for performance of activity. Score range 0-5 point, a high score indicates good upper extremity use frequency and quality of movement during activity. |
| Community Integration Questionnaire | baseline (on the predetermined assessment day) | To assess participation. The total score ranges from 0-29, and the higher the score, the higher the individual's participation in society is considered. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Fatigue Severity Scale | baseline (on the predetermined assessment day) | To assess the severity of fatigue. Score range 1-7 point, a higher score indicates more severe fatigue. |
| Hand Held Dynamometer | baseline (on the predetermined assessment day) | To assess upper extremity muscle strength. Higher scores indicate better muscle strength. |
| Hospital Anxiety and Depression Scale | baseline (on the predetermined assessment day) | To assess anxiety and depression. The total score ranges from 0 to 21 for each of the two subscales. A higher score indicates more severe anxiety and depression. |
| Symbol Digit Modalities Test | baseline (on the predetermined assessment day) | To assess cognitive level. A higher score indicates better cognitive level. |
| Hand Dynamometer | baseline (on the predetermined assessment day) | To assess grip strength. Higher scores indicate better muscle strength. |
| Pinchmeter | baseline (on the predetermined assessment day) | To assess pinch strength. Higher scores indicate better muscle strength. |
| Tuning fork | baseline (on the predetermined assessment day) | To assess deep sense. A higher score indicates better sensitivity. |
| Aesthesiometer | baseline (on the predetermined assessment day) | To assess two-point discrimination. A higher score indicates worse sensitivity. |
Outcome results
None listed