Neuromuscular Manifestations
Conditions
Brief summary
After anesthesia is induced, 2 EMG TOFF devices will be placed on the patients arms, one on the right arm, the other on the left. There will be a randomization per dominant hand and nondominant hand for the placing of the devices. The devices are the Stimpod NMX450X and the Datex-Ohmeda E-NMT.
Interventions
DEVICEEMG TOF device
Use of Stimpod NMX450X as an electromyographic neuromuscular monitor
Sponsors
Universitair Ziekenhuis Brussel
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Intervention model description
Randomization per dominant and nondominant hand. So that there is an even share of number of patients with Stimpod NMX450X on dominant hand and Datex-Ohmeda E-NMT.
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adult patients (18 years old and above) * undergoing General Anaesthesia for noncardiac surgery requiring the use of a neuromuscular blocking agent.
Exclusion criteria
* Use of different types of neuromuscular blocking agents for the same patient within the same surgical procedure. * Known Neuromuscular diseases/syndromes judged to condition accurate neuromuscular monitoring. * Known acute or chronic hepatic disease.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| TOF-ratio (percentage) | Up until 120 minutes | TOF = Train-of-four. TOF-ratio is the ratio of the fourth muscle response to the first one. This is used to assess neuromuscular transmission. TOF% indicates fade in non-depolarizing block. We are comparing the calculated TOF ratio of the stimpod NMX to the datex-ohmeda E-NMT |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| TOF-count (absolute number) | Up until 120 minutes. | TOF count is the actual number of detected muscle responses. The number that is used to calculate the percentage (TOF-ratio). When the TOF count drops below 4 responses, then the TOF% cannot be calculated. We are comparing the detected muscle responses of the stimpod NMX to the datex-ohmeda E-NMT |
Countries
Belgium
Outcome results
None listed