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Incidence and Management of Ocular Hypertension Following Deep Anterior Lamellar Keratoplasty

Incidence and Management of Ocular Hypertension Following Deep Anterior Lamellar Keratoplasty

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04931316
Acronym
Dalk
Enrollment
10
Registered
2021-06-18
Start date
2021-03-15
Completion date
2021-10-20
Last updated
2021-06-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Unrecognized Condition

Brief summary

This is a retrospective case series study that included patients who performed deep anterior lamellar keratoplasty and presented with elevated intraocular pressure during follow up.

Detailed description

This is a retrospective case series study that included patients who performed deep anterior lamellar keratoplasty and presented with elevated intraocular pressure during follow up. Patients' demographic characteristics, medical, and ocular history will be recorded. Inclusion criteria will include patients who were diagnosed with elevated intraocular pressure (IOP) after DALK surgery performed from 2018 to 2020 with follow up duration more than 6 months. Patients with less than 6 months of follow-up will be excluded from the study. Patients' demographic characteristics, medical and ocular history will be recorded. Baseline complete ophthalmic examination was performed. It included best corrected visual acuity (BCVA) using Landolt C chart that was converted to log minimum angle of resolution (log MAR) for statistical analysis, slit lamp anterior segment examination (with attention to cornea, bulbar conjunctiva and AC), intraocular pressure measurement using rebound system (I care tonometer, Topcon, Canada), angle assessment and fundus examination using Goldman 3 mirror contact lens. High IOP was defined as intraocular pressure more than 25 mmHg. Data will be collected with attention to appropriate management done either medical treatment or surgical intervention.

Interventions

OTHERantiglaucoma

use antiglaucoma in ocular hypertension

Sponsors

Mansoura University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
No

Inclusion criteria

* patients who were diagnosed with elevated IOP after DALK surgery performed from 2018 to 2020

Exclusion criteria

* Patients with penetrating keratoplasty

Design outcomes

Primary

MeasureTime frameDescription
Intraocular pressure valuesthis is a retrospective study . collection of data from patients records over 2 monthsassessment of intraocular pressure after lamellar keratoplasty

Countries

Egypt

Contacts

Primary ContactAmgad El Nokrashy, MD
amgad.ali@mans.edu.eg00201022187736
Backup ContactAya Hashish, MD
aya.hashish@mans.edu.eg00201004701791

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026