Traumatic Brain Injury (TBI)
Conditions
Keywords
Traumatic brain injury, TBI, Bloodletting, acupuncture
Brief summary
Traumatic brain injury (Traumatic brain injury, TBI) can be derived from various forms of injury, including blunt trauma, penetrating or acceleration/deceleration force caused by head injury.There are some study data show that acupuncture treatment has a superficial effect on the prognosis of traumatic brain injury and can limit the progression of secondary brain injury, but the effect of early bloodletting at the Jing-points on TBI patients still unknown. In our study, the investigators have proposed a randomized, controlled study design and plan to evaluate the efficacy and safety of Jing-point puncture to improve consciousness and neurological function in patients with TBI. In addition, an objective meridian instrument analysis was added to analyze the energy distribution in the meridian of TBI patients.
Interventions
OTHERacupuncture and bloodletting
bloodletting at the well points of both hands and feet and acupuncture in DU26, DU24 3 times per week for 4 weeks, total 12 treatments.
Sponsors
Chang Gung Memorial Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
20 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
1. Patient with moderate to severe head injury are admitted to the ICU (Intensive Care Unit). patient with stable vital sign and the GCS (Glasgow coma volume) between 5-13 will be included. 2. Patient with normal consciousness and no cognitive or motor function disease before brain injury. 3. Patient aged between 20 to 80 years old and is willing to sign the consent (the agent can sign on behalf of patient).
Exclusion criteria
1. Patients who are vital sign unstable and with severe complication. 2. Patients combined with other terminal illness such as cancer in terminal stage, liver failure, end stage renal failure and so on. 3. Pregnant patients. 4. Any other conditions deemed unsuitable by the physician in charge. 5. Patients (agent of the patient) who did not sign the consent.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| GCS(Glasgow Coma Scale) | 4 weeks | To assess the recovery of consciousness. Lower GCS scores are correlated with higher risk of death. |
| Barthel index | 4 weeks | To assess the activities of daily life. |
| Muscle power | 4 weeks | To assess the recovery of muscle power. |
| mGOS(Modified Glasgow Outcome Score) | 4 weeks | To assess the neurological outcomes, score 1 to 5. the higher the score, the better outcome. |
| RTS (Revised Trauma Score) | 4 weeks | To assess the physiologic condition of patients. The Revised Trauma Score is made up of a three categories: Glasgow Coma Scale, systolic blood pressure, and respiratory rate. The score range is 0-12. A lower score indicates a higher severity of injury. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Meridian energy assessment | 4 weeks | To assess meridian energy by Meridian Energy Analysis Device (M.E.A.D. ) |
Countries
Taiwan
Contacts
Primary Contactwei Ling Chou
Outcome results
None listed