Beta Thalassemia
Conditions
Brief summary
Heart failure from myocardial iron deposition is a severe complication for patients with transfusion-dependent beta thalassemia . Increased cardiac iron content impacts the contractility of cardiomyocytes and can also lead to myocarditis, pericarditis, and arrhythmias. The severity of cardiac dysfunction depends on the amount of iron deposited in the myocardium.Echocardiogram is used as noninvasive method to observe heart status. The objective of this study is to evaluate the heart status in patients of Beta Thalassemia from southern China.
Interventions
DIAGNOSTIC_TESTEchocardiogram and Hematological Analysis
Echocardiogram and Hematological Analysis
Sponsors
ZhuHai Hospital
Shenzhen Children's Hospital
Shenzhen Second People's Hospital
Jiangmen Maternity and Child Health Care Hospital
Yongzhou Maternity and Child Health Hospital
Nanfang Hospital, Southern Medical University
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Inclusion criteria
* Diagnosed with beta-thalassemia
Exclusion criteria
* Iron deficiency anemia
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Echocardiogram | 3 years | Evaluation of heart function in beta thalassemia patients by left ventricular fraction shortening |
Countries
China
Contacts
Primary ContactXiangmin Xu, Prof. Dr.
Outcome results
None listed