Retinal Microvasculature Before and After Silicone Oil by OCTA

Evaluation of Retinal Microvasculature Before and After Silicone Oil Removal by Optical Coherence Tomography Angiography

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04928196

Enrollment

Registered

2021-06-16

Start date

2021-07-12

Completion date

2022-10-15

Last updated

2023-03-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Retinal Vascular

Keywords

retinal microvasculature, microperimtry, OCTA, Silicone oil

Brief summary

Prospective study to assess the retinal microvasculature, optic nerve head vasculature and retinal sensitivity using OCTA and microperimetry before and after silicone oil removal.

Detailed description

Prospective study to assess the retinal microvasculature, optic nerve head vasculature and retinal sensitivity using OCTA and microperimetry before and after silicone oil removal. The study includes 30 patients with silicone oil tamponade will be evaluated before and after silicone oil removal

Interventions

OTHERMicroperimtery and optical coherence tomography angiography OCTA

observational: Investigations are done to assess the retinal microvasculature and function before and after silicone oil removal

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Yes

Inclusion criteria

* 30 eyes of 30 patients with silicone oil tamponade will be evaluated before and after silicone oil removal

Exclusion criteria

* Proliferative diabetic retinopathy, recurrent detachment or macular hole * Patients with chorioretinal degenerations involving the macula * Secondary complications as cataract, silicone oil emulsification, or secondary glaucoma * Media opacity hindering proper imaging

Design outcomes

Primary

Measure	Time frame	Description
Macular and optic nerve head vascular density	one year	Using OCTA to assess vascular density changes of the macula and optic nerve head before and after silicone oil removal
Retinal sensitivity by microperimetry	one year	Using microperimetry to assess the retinal sensitivity changes before and after silicone oil removal

Secondary

Measure	Time frame	Description
Retinal vascular density and best corrected visual acuity	one year	Correlate the change in the retinal vascular density with best corrected visual acuity
Optic nerve head vascular density and best corrected visual acuity	one year	Correlate the change in the optic nerve head vascular density with best corrected visual acuity
Retinal sensitivity and best corrected visual acuity	one year	Correlate the change in the retinal sensitivity with best corrected visual acuity

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 9, 2026