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Risk Factors for Long-term Opioid Use

Opioid Use Among Patients With Pain Syndromes Commonly Seeking Surgical Consultation

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04928131
Enrollment
1500392
Registered
2021-06-16
Start date
2007-01-31
Completion date
2021-02-28
Last updated
2022-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain Syndrome

Brief summary

Surgeons often see patients with pain to exclude organic pathology and consider surgical treatment. We examined factors associated with long-term opioid therapy among patients with foot/ankle, anorectal, and temporomandibular joint pain to aid clinical decision making. Using the IBM MarketScan® Research Database, we conducted a retrospective cohort analysis of patients aged 18-64 with a clinical encounter for foot/ankle, anorectal, or temporomandibular joint pain (January 2007-September 2015). Multivariable logistic regression was used to estimate adjusted odds ratios for factors associated with long-term opioid therapy, including age, sex, geographic region, pain condition, psychiatric diagnoses, and surgical procedures in the previous year.

Interventions

OTHERNo intervention - retrospective observational cohort study

Sponsors

Stanford University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 64 Years

Inclusion criteria

* 18-64 years old * at least one encounter for anorectal, foot/ankle, or TMJ pain * Marketscan continuous enrollment for 1 year prior and 1 year after the index pain encounter

Design outcomes

Primary

MeasureTime frameDescription
Long-term opioid use>90 days of opioid supplyopioid prescriptions for 3 months.

Secondary

MeasureTime frameDescription
new long-term opioid use>90 days of opioid supplyOpioid prescriptions for over 3 months in patients who have not had prior opioid prescriptions.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026