Placenta Accreta Spectrum
Conditions
Keywords
Placenta Accreta Spectrum, Autologous Blood Cell Transfusion, Blood Components
Brief summary
Placenta accreta spectrum (PAS) disorders are associated with increased maternal morbidity and mortality related to life-threatening hemorrhage, and greater potential need for blood transfusion. Clinical evidences have confirmed that the use of autologous blood cell transfusion is safe and effective for patients with obstetric haemorrhage. Normal saline is the solution recommended for red cell washing, administration and salvage. However, there is growing concern that normal saline is more toxic than balanced, buffered crystalloids such as Lactated Ringer's and Plasma-Lyte. The purpose of this study is to evaluate the blood components using of Ringer's Lactated by a prospective, single-center, open, and single-arm clinical trial.
Interventions
OTHERRinger's Lactated
Using of Ringer's Lactated In Autologous Blood Cell Transfusion
Sponsors
Maternal and Child Health Hospital of Foshan
Study design
Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 45 Years
Healthy volunteers
No
Inclusion criteria
* Between 18 and 45 years old * Without health problem nor disease requiring regular medical treatment
Exclusion criteria
* subject with contraindication for drawing blood * Subject with physical or mental disability or restriction of liberty that would prevent autotransfusion
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in hematological parameters | Baseline (Day 1), until 2 days after autotransfusion | erythrocytes (/µL) |
Countries
China
Outcome results
None listed