Supramaximal Rectus Recession for Strabismus in Grave's Ophthalmopathy

The Management of Large-angle Strabismus in Grave's Ophthalmopathy With Supramaximal Rectus Recession

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04927468

Enrollment

Registered

2021-06-16

Start date

2021-07-01

Completion date

2023-07-01

Last updated

2021-06-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Graves Ophthalmopathy, Strabismus, Mechanical

Brief summary

The purpose of this study is to evaluate supramaximal rectus recession for strabismus in Grave's Ophthalmopathy

Detailed description

To evaluate the effectiveness and complications of supramaximal rectus recession for large-angle strabismus in Grave's Ophthalmopathy

Interventions

PROCEDUREsupramaximal rectus recession

inferior rectus recession is 10mm，medial rectus recession is 9mm,superior rectus recession is 14mm for large-angle strabismus

PROCEDUREnormal rectus recession

inferior rectus recession is 7mm，medial rectus recession is 7mm,superior rectus recession is 7mm for large-angle strabismus

Study design

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Clinical diagnosis of Grave's ophthalmopathy * angle of deviation more than 20° * clinically and biochemically euthyroid for at least 3 months; * a stable orthoptic examination for at least 3 months, for example no greater than five prism dioptre change in primary position and no greater than an 8° change in duction * monocular and mainly single extraocular muscle restricted motility

Exclusion criteria

* Patients with suppression, previously diagnosed and/or treated strabismus not related to the thyroid * best-corrected visual acuity (BCVA) less than 0.2 in one or both eyes

Design outcomes

Primary

Measure	Time frame	Description
Postoperative deviations	6 weeks	Postoperative deviations in the primary position were measured in prism diopters

Secondary

Measure	Time frame	Description
binocular single vision	6 weeks	measure the triple visual function including simultaneous vision, fusion range and distance stereoacuity with synoptophore.
stereoacuity	6 weeks	measure near stereoacuity in downgaze position and distance stereoacuity in primary position with random-dot stereopsis.
ocular motility	6 weeks	evaluate the ocular motility with fixed visual field examination ,scaled from -4 to +4

Contacts

Primary ContactYang Huasheng

yanghs64@163.com+00862087331539

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026