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Nudges for Opioid Reduction After Major Surgery Trial

Nudges for Opioid Reduction After Major Surgery

Status
Active, not recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04927351
Acronym
NORMS
Enrollment
484
Registered
2021-06-16
Start date
2021-11-17
Completion date
2024-12-01
Last updated
2024-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Surgery

Keywords

Surgery, Discharge, Hospital Systems, Electronic Medical Record, Opioids, Prescription

Brief summary

This is a prospective pilot trial to evaluate a new electronic medical record based intervention to improve discharges after surgery. The investigators hypothesize that standard discharge medications after surgery will help to optimize opioid prescribing and potentially decrease healthcare utilization in the first 30 days after surgery.

Detailed description

This is a 2-arm parallel randomized trial comparing a new electronic medical record (EMR)-based intervention to usual care after surgery. All patients will receive their usual peri- and intraoperative care. Then, upon discharge, their providers will see the new EMR-based discharge order set (intervention arm) or not (usual care). The investigators hypothesize that standard discharge medication order sets after surgery will help to optimize opioid prescribing and potentially decrease healthcare utilization in the first 30 days after surgery.

Interventions

BEHAVIORALElectronic Medical Record Based Discharge Medication Order Set

New medication discharge order set including recommended opioid quantities, adjunct pain medication

Sponsors

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
CollaboratorNIH
University of Washington
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE

Intervention model description

2 arm parallel, cluster-randomized trial

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Adult patients * Aged 18 and over * Undergo selected general surgical procedures

Exclusion criteria

* Less than 18 years of age

Design outcomes

Primary

MeasureTime frameDescription
Total Discharge Opioid BurdenImmediately after study interventionMorphine milligram equivalents in the initial discharge prescription after index surgery

Secondary

MeasureTime frameDescription
Additional Opioid Burden within 30 daysWithin 30 DaysMorphine milligram equivalents on any additional opioid prescription within 30 days of discharge
Proportion of cases with Phone Calls to Surgery DepartmentWithin 30 DaysPhone calls to surgery department within 30 days of discharge
Proportion of Cases with Emergency Room VisitsWithin 30 DaysER visits within 30 days of discharge
Proportion of Cases with Hospital Readmissions to a Surgical ServiceWithin 30 DaysReadmissions to surgical service within 30 days of discharge

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026