Gustatory Modulators Among a Sample of Depressed Egyptian Adults Under Anti-depressants Therapy

Gustatory Modulators Among a Sample of Depressed Egyptian Adults Under Anti-depressants Therapy. A Retrospective Cohort Study

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04923425

Enrollment

Registered

2021-06-11

Start date

2020-02-22

Completion date

2020-10-07

Last updated

2021-06-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Taste Disorders

Brief summary

Identify possible modulators for developing gustatory dysfunction among a sample of depressed Egyptian adults (age from 20 to 50 years old) under anti-depressants therapy ( for at least 3 months) using a questionnaire ( appendix) with a binary measuring unit (yes/no).

Detailed description

PECO * P Population: depressed Egyptian adults under anti-depressants therapy * E1 Exposure 1: commonly prescribed tricyclic antidepressants (Imipramine, Amitriptyline, Clomipramine HCL) * E2 Exposure 2: commonly prescribed Selective Serotonin Re-uptake inhibitors antidepressants ( Fluoxetine, Fluvoxamine, Sertraline, Citalopram, Paroxetine) * C control (non exposure) : non-pharmacological treatment ( psychotherapy) * O Outcome: Identify possible gustatory dysfunction modulators among these patients using a questionnaire ( appendix) with a binary measuring unit (yes/no).

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

20 Years to 50 Years

Healthy volunteers

Inclusion criteria

* • Depressed Egyptian adults under antidepressants therapy for at least 3 months/non-pharmacological treatment( psychotherapy) * Age from 20 to 50 years old

Exclusion criteria

* Antipsychotics * Hypnotics * Anticonvulsants * Ages other than the mentioned • Olfactory dysfunction * Chemosensory dysfunction

Design outcomes

Primary

Measure	Time frame	Description
Gustatory dysfunction modulators	during a period of 7months from February 2020 till August 2020	-C.M will use an assessment questionnaire (appendix) to assess possible modulators for developing gustatory dysfunction including a number of short-term and long-term factors such as body mass, gender, age, local and systemic diseases, excessive alcohol drinking, drug dependence, smoking, state of oral hygiene, consumption of some foods or drugs

Countries

Egypt

Outcome results