Taste Supra-thresholds Among a Sample of Depressed Egyptian Adult Under Anti-depressants Therapy

Taste Supra-thresholds Among a Sample of Depressed Egyptian Adults Under Anti-depressants Therapy A Retrospective Cohort Study

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04923321

Enrollment

Registered

2021-06-11

Start date

2021-02-22

Completion date

2021-05-07

Last updated

2022-02-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Taste Disorders

Brief summary

Determine the taste intensity at supra-threshold among a sample of depressed Egyptian adults (age from 20 to 50 years old) under anti-depressants therapy ( for at least 3 months) using filter paper disc(FPD) method using a psychophysical method through a scoring system.

Detailed description

PECO * P Population: depressed Egyptian adults under anti-depressants therapy * E1 Exposure 1: Tricyclic antidepressants (Imipramine, Amitriptyline, Clomipramine HCL) * E2 Exposure 2: Selective Serotonin Re-uptake inhibitors antidepressants ( Fluoxetine, Fluvoxamine, Sertraline, Citalopram, Paroxetine) * C control (non exposure) : non-pharmacological treatment ( psychotherapy) * O Outcome: Determine the taste intensity at supra-threshold among these patients using a psychophysical method through a scoring system

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

20 Years to 50 Years

Healthy volunteers

Inclusion criteria

* Depressed Egyptian adults under antidepressants therapy for at least 3 months/non-pharmacological treatment( psychotherapy) • Age from 20 to 50 years old

Exclusion criteria

* Antipsychotics * Hypnotics * Anticonvulsants * Ages other than the mentioned • Olfactory dysfunction * Chemosensory dysfunction

Design outcomes

Primary

Measure	Time frame	Description
Taste intensity at supra-threshold	during a period of 3 months from February 2021 till April 2021]	\- C.M will assess the taste intensity at supra-threshold level on a 9 point vertical labeled scale (extremely strong, very strong, strong, slightly strong, neutral, slightly weak, weak , very weak, extremely weak) in which subjects indicate the intensity perceived when tasting a substance

Countries

Egypt

Outcome results