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Evaluation of Cerebral Venous Return With Internal Jugular Vein Blood Flow in Gynecological Laparoscopic Surgery

Evaluation of Cerebral Venous Return With Internal Jugular Vein Blood Flow in Gynecological Laparoscopic Surgery

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04922060
Enrollment
20
Registered
2021-06-10
Start date
2021-06-08
Completion date
2021-06-30
Last updated
2021-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Internal Jugular Vein (IJV) Blood Flow in Gynecological Laparoscopic Surgery

Keywords

Laparoscopic surgery, cerebral venous drainage, internal jugular vein

Brief summary

The steep Trendelenburg position (STP) provides an advantage in laparoscopic procedures as it optimizes the surgical image. In laparoscopic operations, the need for CO2 pneumoperitoneum (PP), together with this non-physiological position, raises concerns about the patient's physiological homeostasis. Although most patients seem to tolerate the combination of STP and PP, this method carries risks of ICP (intracranial pressure) and brain perfusion. The head-down position increases arterial pressure as well as CVP, thereby disrupting cerebral venous drainage and increasing hydrostatic pressures in the cerebral vascular system. This increases cerebrovascular resistance and decreases cerebral blood flow by increasing ICP and cerebral edema. Systemic CO2 absorption from pneumoperitoneum causes hypercarbia. Hypercarbia can increase cerebral blood flow through cerebral vasodilation. Seventy-four percent to 95% of cerebral venous drainage in the supine position is provided by IJVs. Studies have shown that IJVs, which are responsible for most cerebral venous drainage, exhibit changes in diameter and blood flow due to TP. These studies were generally conducted on moderate TP and on healthy volunteers. In this study, we aim to evaluate the effects of a steep Trendelenburg position (25°) and pneumoperitoneum on IJV blood flow in patients undergoing operation under general anesthesia

Interventions

None listed

Sponsors

Selcuk University
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Age
18 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

ASA I-II physical status age between 18 and 65 years planned gynecological laparoscopic surgery. -

Exclusion criteria

history of head and neck surgery history of cerebrovascular disease ASA III-IV physical status \-

Design outcomes

Primary

MeasureTime frameDescription
Change in internal jugular vein blood flow in laparoscopic gynecological cases90 minuteto evaluate the effects of the pneumoperitoneum (PP) and steep Trendelenburg position (STP) on cerebral venous return with internal jugular vein (IJV) blood flow in gynecological laparoscopic surgery

Contacts

Primary Contactemine ASLANLAR
draslanlar@gmail.com05556219830
Backup ContactMehmet SARGIN
mehmet21sargin@yahoo.com05322662766

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026