Ventricular Arrhythmias
Conditions
Keywords
Signal Averaging ECG, Cardiac electrophysiology
Brief summary
Cardiac electrical activity is detected on the body surface with conventional electrocardiography involving 12 leads (ECG 12). A limitation of the current ECG technique is that recordings are obtained from only 6 independent precordial leads pairs ; which may miss cardiac potentials from spatially limited regions. More extensive sampling of the body surface may contribute to additional clinical information. The present study investigates the additional sensitivity of ECG using 128 body surface leads (High Density (HD) ECG) in measuring global or regional cardiac activity.
Interventions
DEVICEHD ECG
This experimental procedure is a passive, non-invasive, high-density surface ECG recording using 128 skin electrodes.The electrodes are positioned on strips of 10 electrodes to be prepared with adhesive tape and coated with conductive gel before installation on the patient. The total duration of the acquisition is 10 to 30 minutes.
DEVICEConventional 12-lead ECG
This standard 12-lead ECG is defined on the HD ECG, from electrodes F13, G3, G14, H5, H15, H25 corresponding to the precordial electrodes. 4 limb electrodes will be added for the frontal leads. Thus, the HD and 12-lead ECGs will be obtained simultaneously.
Sponsors
University Hospital, Bordeaux
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE
Intervention model description
Prospective single arm monocentric descriptive and evaluation study.
Eligibility
Sex/Gender
ALL
Age
14 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patient managed at the Bordeaux University Hospital for assessment of documented severe ventricular arrhythmia (VF, sudden resuscitated death) or suspected (syncope, family history of sudden death, ECG or Holter abnormality) or impaired ventricular conduction, OR * Patients managed for prophylactic ventricular defibrillator implantation, according to international recommendations: Heart disease with ejection fraction \< 35%, heart disease with sustained ventricular tachycardia, cardiomyopathies with high rhythmic risk, * Women of childbearing age with effective contraception.
Exclusion criteria
* patients under 14 years old, * pregnant or nursing woman.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Identification of anatomical locations electrical criteria by HD ECG | Day 0 | Defined by the position of the electrodes |
| Identification of the amplitude electrical criteria by HD ECG | Day 0 | These electrical criteria are measured in millivolt (mV) |
| Identification of the cardiac time electrical criteria by HD ECG | Day 0 | Defined by the auricular cardiac time, ventricular depolarization and repolarization time |
| Identification of the duration electrical criteria by HD ECG | Day 0 | These criteria are measured in milliseconds (ms) |
Countries
France, Monaco
Contacts
Primary ContactMichel HAÏSSAGUERRE, MD-PhD
Backup ContactAude CATHALA
Outcome results
None listed