Kidney Injury, Acute, Transcatheter Aortic Valve Implantation
Conditions
Keywords
renal regional oxygen saturation, acute kidney injury, transcatheter aortic valve implantation
Brief summary
This prospective observational study evaluates the association of peri-procedural changes in renal regional oxygen saturation and post-procedural acute kidney injury in patients undergoing transcatheter aortic valve implantation.
Detailed description
This prospective observational cohort study evaluated the association of renal regional oxygen saturation, measured during transcatheter aortic valve implantation, and post-procedural acute kidney injury. Renal regional oxygen saturation is measured using near-infrared spectroscopy on the skin surface over the kidneys.
Interventions
DEVICERegional oxygen saturation monitoring
Regional oxygen saturation of kidney is monitored using near infrared spectroscopy
Sponsors
Seoul National University Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
20 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adult patients (\>= 20 years old) undergoing transcatheter (transfemoral) aortic valve implantation
Exclusion criteria
* Emergent procedure * Pre-procedural severe renal impairment (eGFR \< 30 mL/min/1.73 m2) * Pre-procedural hemodialysis * Distance from skin to renal capsule \> 4 cm * Pre-procedural mechanical ventilation * Refuse to participate
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| acute kidney injury | during 7 days post-TAVI | increase in serum creatinine compared with baseline or reduced urine output |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| composite complication | during 7 days post-TAVI or until discharge | stroke, delirium, acute MI, heart failure, new or worsening arrhythmia, mechanical ventilation over 24 h, length of ICU stay, hospital stay, mortality |
Countries
South Korea
Outcome results
None listed