Heart Rate Response, Orthostasis
Conditions
Keywords
Heart rate response, Active Stand
Brief summary
Study background: Impaired heart rate recovery following active stand is associated with morbidity and mortality. Evidence for the repeatability of this measure is limited. This study seeks to determine the repeatability of the active stand procedure in eliciting heart rate recovery in healthy adults of all ages. Research aims: The aims of this study are to determine the repeatability of heart rate recovery in response to the active stand procedure among different age groups. Study design: This will be a repeatability study with between group comparison. Study setting: This study will take place in the Clinical Research Facility in St James's Hospital. Participants: Participants will be recruited from the staff and student population of Trinity College Dublin and St James's Hospital, from the Trinity Retirement Association and from the community in the St. James's Hospital catchment area. Participants will be healthy adults (over 18 years old). They will be invited to participate via an email and poster campaign. Participation will be fully voluntary. Participants who meet inclusion criteria will be selected. Informed, explicit voluntary consent will be obtained from each participant. Data collection and processing: Data collection and processing will be carried out by the Research Physiotherapist. A clinical visit for the participant will be arranged at a time most convenient for them. Participants will conduct the active stand assessment on three occasions.
Interventions
DIAGNOSTIC_TESTActive Stand
The participant is asked to lie down for 10 mins without moving or speaking. A heart rate monitor is attached while the participant is lying down. They are then asked to stand up as quickly as possible and to remain standing unassisted for 3 minutes. The participant will be asked to describe any symptoms at 1 and 3 minutes after standing. Blood pressure and heart rate will be monitored constantly throughout the test.
Sponsors
Caitríona Quinn
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
Yes
Inclusion criteria
* Healthy adults aged ≥18 (considering 18 is the age of legal consent). * Fluent in English. * Free of intellectual disability or cognitive impairment that would impair or impede the ability to give informed, explicit consent. * Free of all
Exclusion criteria
below.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Baseline Heart Rate | 60 seconds prior to standing assessment | R-R interval is recorded by portable ECG throughout assessment |
| Maximum heart rate | Within 3 minutes of standing assessment | R-R interval is recorded by portable ECG throughout assessment |
| Minimum heart rate | Within 3 minutes of standing assessment | R-R interval is recorded by portable ECG throughout assessment |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Body Mass Index | Day 1 | Kg/m\^2 |
| Body Fat Percentage | Day 1 | Percentage |
| Demographic data | Day 1 | gender, age, relevant past medical history |
| Vascular Stiffness | Day 1 | Pulse Wave Analysis conducted using the Mobil-O-Graph 24-hour Pulse Wave Analysis (PWA) system. |
| Blood Pressure | At baseline | Blood Pressure |
| Height | Day 1 | Centimeters |
| Weight | Day 1 | Kilograms |
Countries
Ireland
Outcome results
None listed