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Assessment of Eyelid Topology and Kinetics Based on Deep Learning Method

Department of Ophthalmology

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04921020
Enrollment
500
Registered
2021-06-10
Start date
2020-08-01
Completion date
2026-08-01
Last updated
2021-06-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Eyelid Diseases

Brief summary

This study plans to assess eyelid topology (such as margin reflex distance, eyelid contour, and corneal exposure area) and blinking (such as frequency, velocity, and duration), using deep learning method to automatically extract eyelid topological features, and to predict subtypes of levator function, using deep learning method to extract blinking features, in order to provide new ideas and means to assess eyelid topology and kinetics.

Interventions

Facial photographs and blinking videos are taken

Sponsors

Second Affiliated Hospital, School of Medicine, Zhejiang University
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Healthy volunteers
Yes

Inclusion criteria

1. normal volunteers without eyelid diseases 2. patients with blepharoptosis 3. patients with blepharospasm 4. patients with dry eye disease 5. patients with Graves' disease

Exclusion criteria

variable ptosis (e.g., myasthenia gravis), entropion, ectropion, enophthalmos, exophthalmos, strabismus, and abnormalities of pupil

Design outcomes

Primary

MeasureTime frameDescription
one-dimensional parameters of eyelid topologythrough study completion, 5 yearsPalpebral fissure length \[Margin reflex distance 1, Margin reflex distance 2\], Lid length \[Upper lid length, Lower lid length\], Multiple mid-pupil lid distances
two-dimensional parameters of eyelid topologythrough study completion, 5 yearsPalpebral fissure area \[Medial area, Corneal area, Lateral area\]
subtypes of levator functionthrough study completion, 5 yearsLevator function is classified into three categories: good, fair and poor

Countries

China

Contacts

Primary ContactJuan Ye
yejuan@zju.edu.cn+86-571-87783897
Backup ContactLixia Lou
loulixia110@zju.edu.cn+86-15088681589

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026