Glaucoma, Open-Angle
Conditions
Brief summary
To compare the effect of intraocular pressure control and the incidence of peripheral anterior synechia between CLASS combined with phacoemulsification and CLASS alone in the treatment of primary open-angle glaucoma
Detailed description
Group A: CO2 Laser-Assisted Sclerectomy Surgery combined with phacoemulsification; Group B: simple CO2 Laser-Assisted Sclerectomy Surgery. The patients were followed up for 1 year. The incidence of peripheral anterior synechia and Intraocular pressure changes at 1 day, 1 week, 1 month, 2 months, 3 months, 6 months and 12 months were observed and compared between the two groups.
Interventions
PROCEDUREphacoemulsification;
Group A: class combined with phacoemulsification
Sponsors
Second Affiliated Hospital, School of Medicine, Zhejiang University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
50 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
* Primary open-angle glaucoma patients with cataract in our Ophthalmic Center; * Topical use of hypotensive drugs in the treatment of poor or intolerable intraocular pressure control; * The patients were aged from 50 to 80 years old, regardless of gender; * Class operation and phacoemulsification were performed; * Patients are able and willing to comply with the research guidance and may complete all visits required by the research; * Informed consent has been signed.
Exclusion criteria
* Allergic to any perioperative medication in this study; * History of ocular trauma; * Any previous intraocular surgery; * Angle of the chamber was narrow by angle microscopy (Schaffer grade III and below); * Patients diagnosed as secondary glaucoma; * Optic atrophy caused by other reasons; * The serious complications such as posterior capsule rupture and choroidal hemorrhage occurred during the operation; * Serious complications of eyes occurred after operation; * The patient's history indicated that he had severe dysfunction of heart, lung, liver and kidney; * Women in pregnancy, lactation or planned pregnancy; * The researchers believe that the patient's condition may put the patient at significant risk, and may confuse the research results.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Incidence of peripheral anterior synechia | 1 year | Incidence of peripheral anterior synechia |
| Intraocular pressure | 1 year | Intraocular pressure |
Countries
China
Contacts
Primary ContactKaijun Wang, MD
Outcome results
None listed