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Efficacy of Stretching on Pain Sensitivity

Efficacy of a Stretching Protocol on Regional and Distant Pain Sensitivity:

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04919681
Enrollment
26
Registered
2021-06-09
Start date
2021-11-04
Completion date
2022-10-20
Last updated
2023-04-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain Threshold

Keywords

Stretching, Pain sensitivity, Range of motion, Exercise adherence

Brief summary

The primary objective of this study is to determine the immediate efficiency of a six weeks regular stretching protocol on regional and distant pain sensitivity. It is hypothesised that regional and distant pain sensitivity will significantly decrease following six weeks of regular stretching. The secondary objective of the study is to determine the effect after four-week cessation of the stretching protocol on regional and distant pain sensitivity. If regional and distant pain sensitivity decrease following regular stretching, it is hypothesised that the analgesic effect will abate following four-week cessation.

Interventions

OTHERStretch exercises

The intervention comprises of six weeks daily bi-lateral static stretching of the knee flexors. Stretches are performed seated on the ground. The participant sits upright on the floor with one leg straight. The sole of the other foot should be placed on the inside of the outstretched leg. The participant leans slightly forward, trying to touch their toes while maintaining full knee extension. Stretching is performed to the point of discomfort, and each stretch is held for 30-seconds for three repetitions.

Sponsors

Bispebjerg Hospital
CollaboratorOTHER
University of Copenhagen
CollaboratorOTHER
Research Unit for General Practice in Aalborg
CollaboratorOTHER
University College of Northern Denmark
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE

Masking description

Participants are blinded to the results of the pressure pain threshold measurements. Participants and examiner are blinded to the results of the range of motion and passive resistive torque measurements.

Intervention model description

Single-blind longitudinal repeated measures study

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes

Inclusion criteria

* Healthy men and women aged 18-65 years are recruited. As part of the screening, volunteers will also be asked to indicate known medical issues or diseases. Participants are included if they have no known medical conditions such as * cognitive impairments, * neurological, * orthopaedic, * or neuromuscular problems that might affect the somatosensory system or preclude stretching exercises or range of motion testing at the knee.

Exclusion criteria

* Individuals who regularly engage in flexibility training (e.g., stretching, tai chi, pilates or yoga) * or use any medication that might affect the somatosensory system, such as pain medication, are excluded.

Design outcomes

Primary

MeasureTime frameDescription
Pain sensitivityBaselineThe primary outcome is pain sensitivity expressed as regional and distant pressure pain thresholds measured by a handheld pressure algometer

Secondary

MeasureTime frameDescription
Range of motionBaselinePassive knee extension range of motion measured by the Biodex system 4 pro isokinetic dynamometer
Passive resistive torqueBaselinePassive resistive torque measured in passive kne extension measured by the Biodex system 4 pro isokinetic dynamometer

Other

MeasureTime frameDescription
Adherence to the stretching protocol6 weeksAdherence to the stretching protocol will be measured using self-reported data from an mHealth app.

Countries

Denmark

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 6, 2026