Persistent Atrial Fibrillation, Sudden Death, Ventricular Tachycardia
Conditions
Keywords
Skin sympathetic nerve activity (SKNA), Electrocardiogram (ECG), Cardiac arrythmia
Brief summary
Sympathetic tone is important in cardiac arrhythmogenesis. The simultaneous recording of sympathetic nerve activity (SNA) and electrocardiogram (ECG) was obtained by invasive method. The purpose of this protocol is to further develop this recording method to turn it into a new non-invasive tool for arrhythmia prediction and detection. This method may also be useful in validating the results of surgical procedures aimed at sympathetic denervation
Interventions
DEVICESKNA recording
The coupled recording of the sympathetic nervous activity of the skin and of an ECG will be carried out using the ME6000 device, CE marked, from the Bittium company. It will be performed for a maximum period of one hour at Day 1, Post-procedure between Day 1 and discharge from hospital, and month 6
Sponsors
University Hospital, Bordeaux
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
\- patient hospitalized at Bordeaux University Hospital for sudden death, ventricular tachycardia, persistent or paroxysmal atrial fibrillation treated by ablation and/or vein of Marshall ethanol infusion
Exclusion criteria
* pregnancy, * patient under 18 year old, * patient with a cardiac stimulation device
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Delay between the discharge of the sympathetic system and the rhythmic event. | Day 1 | Temporal correlation of occurrence of sympathetic electrical event and cardiac arrhythmia by the MacNemar test will be performed. |
Countries
France
Outcome results
None listed